週次 |
日期 |
單元主題 |
第1週 |
9/9 |
課程講解 |
第2週 |
9/16 |
搜尋文獻與訂定題目 |
第3週 |
9/23 |
系友分享<br>
林以立(中研院TIGP 博士候選人):生技創業的啟發
|
第4週 |
9/30 |
蔣汶龍 (碩二) Adipose-Specific Deletion of TFAM Increases Mitochondrial Oxidation and Protects Mice against Obesity and Insulin Resistance. Cell Metabolism 2012; 16:765–776. <br> 穆偉倢 (碩二) Brown-fat Paucity due to Impaired BMP Signalling Induces Compensatory Browning of White Fat. Nature 2013; 495:379-383. |
第5週 |
10/7 |
停課一週 |
第6週 |
10/14 |
黃聖富 (碩二) Obesity-induced Gut Microbial Metabolite Promotes Liver Cancer through Senescence Secretome. Nature 2013; 499:97-101.<br> 詹雅晴 (碩二) A Single Strain of Clostridium butyricum Induces Intestinal IL-10-Producing Macrophages to Suppress Acute Experimental Colitis in Mice. Cell Host & Microbe 2013; 13:711–722. |
第7週 |
10/21 |
修淯琳 (碩一) Exercise AttenuatesM1 Macrophages and CD8+ T Cells in the Adipose Tissue of Obese Mice. Med Sci Sports Exerc 2013; 45:1684-1693. <br> 江厚志 (碩二) Structural Modulation of Gut Microbiota in Life-long Calorie-restricted Mice. Nature Communications 2013;4:2163. |
第8週 |
10/28 |
林家暐 (碩一) Glucocorticoid Paradoxically Recruits Adipose Progenitors and Impairs Lipid Homeostasis and Glucose Transport in Mature Adipocytes. Scientific Reports 2013; 3:2573. <br> 陳奕光 (碩一) Liver Receptor Homolog-1 is Essential for Pregnancy. Nature Medicine 2013; 19:1061-1066. |
第9週 |
11/4 |
黃博暉 (碩一) ROS Play a Critical Role in The Differentiation of Alternatively Activated Macrophages and the Occurrence of Tumor-Associated Macrophages. Cell Research 2013; 23:898-914.<br> 王柏凱 (碩一) PPARc-induced PARylation Promotes Local DNA Demethylation by Production of 5-hydroxymethylcytosine. Nature Communications 2013; 4:2262. <br> 期中考週 |
第10週 |
11/11 |
戴言竹 (碩一) Brown Remodeling of White Adipose
Tissue by SirT1-Dependent Deacetylation of Pparg. Cell 2012; 150:620–632. |
第11週 |
11/18 |
蔡宜廷 (碩一) Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1. Cancer Cell 2013; 23:171–185. |
第12週 |
11/25 |
楊智雯 (碩一) SIRT4 Coordinates the Balance between Lipid Synthesis and Catabolism by Repressing Malonyl CoA Decarboxylase. Molecular Cell 2013; 50:686–698. |
第13週 |
12/2 |
毛嘉慶 (碩一) MicroRNA-627 Mediates the Epigenetic Mechanisms of Vitamin D to Suppress Proliferation of Human Colorectal Cancer Cells and Growth of Xenograft Tumors in Mice. Gastroenterology 2013; 145:437–446. |
第14週 |
12/9 |
李健巍 (碩一) High Fat Diet Exacerbates Neuroinflammation in an Animal Model of Multiple Sclerosis by Activation of the Renin Angiotensin System. Journal of Neuroimmune Pharmacology 2013. |
第15週 |
12/16 |
詹培萱 (碩一) Association Between Specific Adipose Tissue CD4D T-Cell Populations and Insulin Resistance in Obese Individuals. Gastroenterology 2013;145:366–374 |
第16週 |
12/23 |
林亞葳 (碩一) The Microbiome-Gut-Brain Axis during Early Life Regulates The Hippocampal Serotonergic System in A Sex-Dependent Manner. Molecular Psychiatry 2013; 18:666-673. |
第17週 |
12/30 |
期末報告 |
第18週 |
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期末考週 |